Autoimmune hepatitis: Of host and pathogen

✍ Scribed by Eirini I. Rigopoulou; George N. Dalekos

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 49 KB
• Volume: 47
• Category: Article
• ISSN: 0270-9139
• DOI: 10.1002/hep.22002

✦ Synopsis

US screening that were well-defined and identified in two US projections. By using these requirements, we avoided the inclusion of patients with coarse, ill-defined, previously present nodules that correspond to regenerative nodules within a cirrhotic liver. If we had included patients with several nodules, the likelihood that one of them would correspond to HCC would have been higher. If we had to study them all at the same time, we would have had to biopsy all of them, which is a proposal that would not be acceptable, as Song will surely agree.

In summary, we hope that these comments have helped to clarify some of the controversies raised by Caturelli, de Sio, and Song, while also exposing the limitations and benefits that FNB offers in the diagnosis of early HCC. Current research efforts in genomics and proteomics may overcome the need of both pathology interpretation and imaging characterization, but in current clinical practice both tools have to be used in a complementary way.