Autoimmune characteristics in Japanese children diagnosed with type 1 diabetes before 5 years of age
β Scribed by Tatsuhiko Urakami; Junichi Suzuki; Ayako Yoshida; Hiroshi Saito; Mika Wada; Shouri Takahashi; Hideo Mugishima
- Book ID
- 108972645
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 63 KB
- Volume
- 51
- Category
- Article
- ISSN
- 1328-8067
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A total of 614 Jewish patients under the age of 18 with Type 1 (insulin-dependent) diabetes mellitus, diagnosed in Israel during the period 1 January 1965 to 31 December 1979, were identified by exhaustive screening of all possible sources. Mortality experience of this cohort was updated to 31 March
The pattern of insulin secretion was studied in 107 normal individuals aged 5 to 50 years. Intravenous glucose tolerance tests were performed on 64 islet-cell antibody negative siblings of diabetic children and on 43 normal adults. Puberty was staged using Tanner's criteria and subjects were grouped