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Autoimmune and Antitumor Consequences of Antibodies Against Antigens Shared by Normal and Malignant Tissues

✍ Scribed by Philip O. Livingston; Govindaswami Ragupathi; Cristina Musselli


Book ID
110239804
Publisher
Springer
Year
2000
Tongue
English
Weight
63 KB
Volume
20
Category
Article
ISSN
0271-9142

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A mouse monoclonal antibody V-715 was raised against fresh colon cancer tissues. Biochemical analysis elucidated that the antigen defined was adenosine deaminase binding protein (ADBP). In colon cancer cell lines, V-715 was positive in 8 out of 16 differentiated cancers and in 2 out of 8 poorly diff