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Autocrine stimulation of osteoblast activity by Wnt5a in response to TNF-α in human mesenchymal stem cells

✍ Scribed by Briolay, A.; Lencel, P.; Bessueille, L.; Caverzasio, J.; Buchet, R.; Magne, D.


Book ID
118179998
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
634 KB
Volume
430
Category
Article
ISSN
0006-291X

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## Abstract Mesenchymal stem cells produce proinflammatory cytokines during their normal growth. Direct or indirect regulation of bone resorption by these cytokines has been reported. However, the effects of osteogenic conditions—chemical and/or mechanical—utilized during in vitro bone tissue engin