Autocrine Role of Macrophage Inflammatory Protein-1 β in Human T-Cell Lymphotropic Virus Type-I tax-Transfected Jurkat T-Cells
✍ Scribed by Venkatanarayanan Sharma; Shelly L Lorey
- Book ID
- 115588724
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 73 KB
- Volume
- 287
- Category
- Article
- ISSN
- 0006-291X
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## Abstract The Human T‐cell leukemia virus type I (HTLV‐I) non‐structural protein Tax plays a crucial role in cellular transformation. It activates the transcription factors of various cellular genes and interacts with cellular proteins. There is limited data available on the interaction between s
## Abstract Human T‐cell lymphotropic virus type I (HTLV‐I) is the etiologic agent of HTLV‐I‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). High HTLV‐I provirus load and __tax__ mRNA level have been suggested as predictors of disease progression in patients with HAM/TSP, but little i