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Autocrine inhibition of renal epithelial Na+/K+-ATPase by nitric oxide

✍ Scribed by NJ Guzman; M Fang; SS Tang; JR Ingelfinger; LC Garg

Book ID
116155607
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
169 KB
Volume
8
Category
Article
ISSN
0895-7061

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Evidence shows that Na(+)/K(+)-ATPase from kidney, brain and liver is inhibited by nitric oxide (NO) and peroxynitrite anion (ONO(2) (-)), but the mechanism is unknown. The aim of the present work was to study the inhibitory effect of NO and ONO(2) (-) on erythrocyte Na(+)/K(+)-ATPase. Erythrocyte m