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Autocrine Growth Loop of The Epidermal Growth Factor Receptor in Normal and Immortalized Human Bronchial Epithelial Cells

✍ Scribed by Ming-Sound Tsao; Hong Zhu; Jean Viallet


Book ID
115602306
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
153 KB
Volume
223
Category
Article
ISSN
0014-4827

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Heparin inhibition of autonomous growth
✍ Shiwei Li; Gregory D. Plowman; Sharon D. Buckley; Gary D. Shipley πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 952 KB

## Abstract Normal human mammary epithelial cells (HMECs) proliferate in a serum‐free defined growth medium in the absence of epidermal growth factor (Li and Shipley, 1991). Amphiregulin (AR) is a heparin‐regulated, EGF‐like growth factor. Our observation that one strain of HMECs produce AR mRNA (C