Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by rapid progression, invasiveness, and resistance to treatment. It is the fourth leading cause of cancer death with a 2% 5-year survival rate. Biomarkers for its early detection are lacking. This study was desig
Autoantibody Signature in Human Ductal Pancreatic Adenocarcinoma
✍ Scribed by Tomaino, Barbara; Cappello, Paola; Capello, Michela; Fredolini, Claudia; Ponzetto, Antonio; Novarino, Anna; Ciuffreda, Libero; Bertetto, Oscar; De Angelis, Claudio; Gaia, Enzo; Salacone, Paola; Milella, Michele; Nisticò, Paola; Alessio, Massimo; Chiarle, Roberto; Giuffrida, Maria G.; Giovarelli, Mirella; Novelli, Francesco
- Book ID
- 126005544
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 295 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1535-3893
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## Abstract ## Background The strongest risk factors for pancreatic adenocarcinoma are tobacco smoking and increasing age. However, only a few smokers or elderly individuals develop the disease and genetic factors are also likely to be important. ## Methods The literature on genetic factors modi