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Autoantibody responses to melanocytes in the depigmenting skin disease vitiligo

✍ Scribed by E. Helen Kemp; Nikos G. Gavalas; David J. Gawkrodger; Anthony P. Weetman

Book ID
113481874
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
129 KB
Volume
6
Category
Article
ISSN
1568-9972

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Vitiligo is a skin disorder characterized by depigmented macules secondary to melanocyte loss. An unusual facet is its relation to melanoma: Cytotoxic T lymphocytes directed to melanocyte antigens are found in both conditions and imply a breakdown of tolerance, yet the resulting immune reaction is t