Autoantibody response to a novel tumor-associated antigen p90/CIP2A in breast cancer immunodiagnosis
β Scribed by Liu, Xinxin; Chai, Yurong; Li, Jitian; Ren, Pengfei; Liu, Mei; Dai, Liping; Qian, Wei; Li, Wenjie; Zhang, Jian-Ying
- Book ID
- 121578089
- Publisher
- S. Karger AG
- Year
- 2014
- Tongue
- English
- Weight
- 447 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1010-4283
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π SIMILAR VOLUMES
We have previously reported the production of a new monoclonal antibody (MAb) (SP-2) recognizing a 90-kDa tumorassociated antigen, termed 9OK. which is increased in the serum of many cancer patients. Treatment of CG5 human breast cancer cells with recombinant interferon-a 2b (rlFN-a 2b) can increase
It has been shown that a 90-kDa protein (90K). with an as yet unknown function, is expressed in the majority of human breast-cancer tissues. In addition, the serum level of this 90K antigen is elevated in a certain proportion of breast-cancer patients, and high serum levels are associated with a poo