Autoantibodies to pyruvate dehydrogenase complex in patients with systemic sclerosis
✍ Scribed by Manabu Fujimoto; Shinichi Sato; Hironobu Ihn; Kanako Kikuchi; Kunihiko Tamaki; Kazuhiko Takehara
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 495 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0004-3591
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📜 SIMILAR VOLUMES
## Abstract Normal activity of the pyruvate dehydrogenase complex was found in platelet‐enriched preparations from two siblings with Friedreich's ataxia who had been reported previously as being deficient in this enzyme.
Communicated by
## Abstract ## Objective Fibroblasts play a crucial role in the development of systemic sclerosis (SSc), and antifibroblast antibodies (AFAs) capable of inducing a proinflammatory phenotype in fibroblasts have been detected in the sera of SSc patients. This study examined the prevalence of AFAs in