Autoantibodies to M2 mitochondrial autoantigens in normal human sera by immunofluorescence and novel assays

Detection of autoantibodies to ss-a/ro b

Detection of autoantibodies to ss-a/ro by indirect immunofluorescence using a transfected and overexpressed human 60 kd ro autoantigen in hep-2 cells

✍ Dr. Marvin J. Fritzler; B. Joan Miller 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 845 KB

The objective of the study was to determine the sensitivity and specificity of an indirect immunofluorescence (IIF) assay using transfected HEp-2 cells to detect anti-SS-A/ Ro autoantibodies in human sera. Seventythree sera having SS-NRo autoantibodies as determined by double immunodiffusion (ID) an