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Autoantibodies to ion channels at the neuromuscular junction

✍ Scribed by Bethan Lang; Angela Vincent


Book ID
117799158
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
364 KB
Volume
2
Category
Article
ISSN
1568-9972

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Clustering of sodium channels at the neu
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Voltage-gated sodium channels (NaChs) are highly concentrated in the postsynaptic region of the neuromuscular junction, especially in the depths of postsynaptic folds and in the perijunctional region. The formation of the high NaCh density occurs during synapse maturation, approximately 2 weeks afte