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Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis

✍ Scribed by M. DIEUDÉ; M.-A. GILLIS; J.-F. THÉORÊT; E. THORIN; G. LAJOIE; J. S. LEVINE; Y. MERHI; J. RAUCH


Book ID
109152862
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
818 KB
Volume
7
Category
Article
ISSN
1538-7933

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✍ Mélanie Dieudé; José A. Correa; Carolyn Neville; Christian Pineau; Jerrold S. Le 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 1 views

## Abstract ## Objective Anti–heat shock protein 60 autoantibodies (anti‐Hsp60) are associated with cardiovascular disease and are known to affect endothelial cells in vitro, and we have recently shown that anti‐Hsp60 promote thrombosis in a murine model of arterial injury. Based on those findings