Autoantibodies against nucleoporin p62 constitute a novel marker of primary biliary cirrhosis
β Scribed by J Wesierska-Gadek; H Hohenuer; E Hitchman; E Penner
- Book ID
- 119755317
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 637 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0016-5085
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## Abstract Reactivity of sera from patients with primary biliary cirrhosis (PBC) with a 60 kDa component of nuclear pore complexes (NPCs), purified by affinity chromatography on wheatβgerm agglutinin (WGA)βSepharose, was previously detected. Recently, clinical significance of the antiβNPC antibodi
Antinuclear antibodies (ANA) staining nuclear dot structures predominantly occur in primary biliary cirrhosis (PBC) patients and recognize the Sp100 and promyelocytic leukemia protein (PML). From retrospective analysis of sera from a clinically well-defined Canadian series of 170 PBC patients includ