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Autoantibodies against nuclear envelope-associated proteins in primary biliary cirrhosis

✍ Scribed by Dr. Francisco Lozano; Albert Parés; Luis Borche; Montserrat Plana; Teresa Gallart; Joan Rodés; Jordi Vives

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
899 KB
Volume
8
Category
Article
ISSN
0270-9139

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✦ Synopsis

An antinuclear immunofluorescence pattern displaying a thin ring confined to the nuclear envelope was assessed in sera from 38 patients with primary biliary cirrhosis and in sera from a control group of 277 patients with other antinuclear antibody-positive diseases. This rim-like antinuclear reactivity was present in sera from 20 primary biliary cirrhosis patients (52.6%) but in only two patients from the control group (0.7%) (p <

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