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Autoantibodies against liver cell membrane antigens detected by enzyme-linked immunosorbent assay in acute and chronic liver disease

✍ Scribed by Yoshiyuki Ohtani; Shinichi Kakumu; Akihiko Fuji; Kenichi Murase

Book ID
118374857
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
847 KB
Volume
43
Category
Article
ISSN
1090-2341

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In this study, we describe a radioimmunoassay to detect liver membrane binding antibodies. The assay was designed to exclude binding of aggregated IgG or immune complexes to Fc y receptors of hepatocytes. When this assay was applied to sera from 142 patients, antibodies were found in highest titer i