Auto-immunity in children with diabetes mellitus and in their relatives
β Scribed by R. Lorini; D. Larizza; C. Livieri; V. Cammareri; A. Martini; A. Plebani; D. Zanaboni; F. Severi
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 325 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0340-6997
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Binding capacity for porcine, bovine, and human insulin was estimated in 104 diabetic children using homologous systems of iodinated and noniodinated insulin. All patient sera bound porcine and bovine insulin whilst 11.5~o did not bind human insulin. There was no clear correlation between duration o
We investigated autonomic function in 58 children and young adults with Type 1 diabetes mellitus (aged 7-22 years, duration from 3 to 18, 8.6 Β± 3.4 years) and in 74 healthy controls (6-21 years) using power spectral analysis of blood pressure and heart rate in addition to conventional standard auton
## Abstract Palpable thickening and induration of the skin of the fingers were found in 47 (34%) of 137 children with insulinβdependent diabetes mellitus and in none of 52 normal children. Mild flexion contractures of the interphalangeal joints were seen in 26 (19%), mainly in those children with m