Autism Spectrum Disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1

Autism spectrum disorder is related to e

Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1

✍ Fujita, E; Dai, H; Tanabe, Y; Zhiling, Y; Yamagata, T; Miyakawa, T; Tanokura, M; 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 473 KB

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with an unknown molecular pathogenesis. A recent molecular focus has been the mutated neuroligin 3, neuroligin 3(R451C), in gain-of-function studies and for its role in induced impairment of synaptic function, but endoplasmic reticulum