A recent article by Hotta and colleagues 1 reports that survival of patients with nonsmall cell lung cancer (NSCLC) improved slowly over time from 1982 to 2002. Authors pooled together 121 phase 3 trials (42,768 patients overall),
Author reply to recent improvement in the survival of patients with advanced nonsmall cell lung cancer enrolled in phase III trials of first-line, systemic chemotherapy
β Scribed by Katsuyuki Hotta; Yoshiro Fujiwara; Keitaro Matsuo
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 38 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND This is a phase 2 study of chemotherapyβnaive patients, 70 years of age or older, with nonsmallβcell lung cancer (NSCLC) who were treated with docetaxel and gefitinib. The primary endpoint was response rate (RR). Secondary endpoints were overall survival (OS) and progress
## Background: Pemetrexed disodium (alimta [eli lilly and company, indianapolis, in], ly231514, multitargeted antifolate) is a new multitargeted antifolate agent that inhibits multiple enzymes in the folate pathway. phase ii trials showed single-agent response rates of 16% and 23% in untreated pati