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Authenticity of 2,6-Dichloro-1,5-naphthyridine

✍ Scribed by George R. Newkome; Sam J. Garbis


Book ID
112125344
Publisher
Journal of Heterocyclic Chemistry
Year
1978
Tongue
English
Weight
86 KB
Volume
15
Category
Article
ISSN
0022-152X

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Preparation of 1,6-naphthyridine-2,5(1H,
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## Abstract Novel method for the synthesis of 3‐acyl‐1,6‐dialkyl‐7‐methyl‐1,6‐naphthyridine‐2,5(1H,6H)‐diones (2) was developed. The reaction of 2‐acyl‐1‐alkylamino‐1‐ethoxyethylenes (1) with acetyl chloride or β‐keto amide **3** with acetyl chloride in the presence of __p__‐toluenesulfonic acid ga