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Aurora A phosphorylation of the epigenetic regulator HP1γ mediates cell division in pancreatic cancer cells

✍ Scribed by Grzenda, A.; Leonard, P.; Urrutia, G.; Mathison, A.; Fernandez-Zapico, M.; Urrutia, R.; Lomberk, G.

Book ID
122581722
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
46 KB
Volume
13
Category
Article
ISSN
1424-3903

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## Abstract Pancreatic cancer is a highly aggressive malignancy and one of the leading causes of cancer deaths, mainly due to the lack of methods for early diagnosis and the lack of effective therapies. Recent CGH microarray studies have revealed several regions that are recurrently amplified in pa