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Augmented antitumour effects of combination therapy with TNP-470 and chemoimmunotherapy in mice

✍ Scribed by Anna Dabrowska-Iwanicka; Dominika Olszewska; Ahmad Jalili; Marcin Makowski; Tomasz Grzela; Maria Marczak; Grazyna Hoser; Adam Giermasz; Jakub Golab; Marek Jakóbisiak

Publisher: Springer-Verlag
Year: 2002
Tongue: English
Weight: 269 KB
Volume: 128
Category: Article
ISSN: 1432-1335
DOI: 10.1007/s00432-002-0356-z

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## Abstract Lovastatin, the drug used for the treatment of hypercholesterolemia, has previously been reported to exert antitumor activity in experimental murine models. Butyrate and butyric acid derivatives are well known to induce differentiation and apoptosis of tumour cells and also have recentl