Augmentation of specific immune response against syngeneic SV40-induced tumor-associated antigens by splenectomy
β Scribed by Moshe Glaser
- Book ID
- 115811845
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 511 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0008-8749
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Highly purified vesicular stomatitis virus (VSV) was obtained from VSV-infected SV40-transformed and from "normal" hamster cell lines. A glycolipid extract was prepared from these VSV preparations according to the Folch partition procedure. These glycolipids were rendered immunogenic to the Syrian h
## Abstract The role of adherent phagocytic cells in an __in vitro__ secondary cytotoxic response against Simian virus 40 (SV40)βinduced tumorβassociated antigens was investigated. Spleen cells (responder cells), from mice primed with syngeneic SV40βtransformed cells, extensively depleted of macrop