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Augmentation of mixed lymphocyte response stimulatory activity by phorbol ester

✍ Scribed by Jun Okamura; Michelle Letarte; Erwin W. Gelfand


Book ID
105003368
Publisher
Springer
Year
1984
Tongue
English
Weight
750 KB
Volume
4
Category
Article
ISSN
0271-9142

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The phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and the calcium ionophore, A23187, have similar effects on many different cells. For example, both show mitogenic and comitogenic activities for lymphocytes. It had been suggested that some of TPA's effects are due to its ab