## Background Thalassaemia major (TM) patients need regular blood transfusions that lead to accumulation of iron and death from heart failure. Deferiprone has been reported to be superior to deferoxamine for the removal of cardiac iron and improvement in left ventricular (LV) function but little is
Augmentation of Left Atrial Contractile Function: A Herald of Iron Overload in Patients with Beta Thalassemia Major
β Scribed by Reza Shabanian; Giv Heidari-Bateni; Armen Kocharian; Mehdi Mashayekhi; Shahriar Hosseinzadeh; Abdolrazagh Kiani; Mina Izadyar; Leila Koochakzadeh
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 211 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0172-0643
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## Abstract ## Purpose To compare left ventricular (LV) diastolic function with myocardial iron levels in beta thalassemia major (TM) patients, using cardiovascular magnetic resonance (CMR). ## Materials and Methods We studied 67 regularly transfused patients with TM and 22 controls matched for
Function normalized to the body surface area, age and gender from CMR in a large cohort of well-treated Thalassemia Major patients without myocardial iron overload.