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Augmentation of immune responses to SARS coronavirus by a combination of DNA and whole killed virus vaccines

✍ Scribed by Alexander N. Zakhartchouk; Qiang Liu; Martin Petric; Lorne A. Babiuk


Book ID
116958089
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
207 KB
Volume
23
Category
Article
ISSN
0264-410X

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## Abstract Integrins are critical for initiating T‐cell activation events. The integrin‐binding motif Arg‐Gly‐Asp (RGD) was incorporated into the pcDNA 3.1 mammalian expression vector expressing the codon‐optimized extracellular domain of SARS coronavirus (SARS‐CoV) spike protein, and tested by im