Auer bodies in acute lymphocytic leukaemia and B-cell lymphoma: Evidence for a common progenitor of myeloid and lymphoid cells?

✍ Scribed by Jehn, U. ;Thiel, E.

• Publisher: Springer-Verlag
• Year: 1981
• Weight: 889 KB
• Volume: 43
• Category: Article
• ISSN: 1432-0584
• DOI: 10.1007/bf00319926

✦ Synopsis

In a patient with acute lymphocytic leukaemia (pre-T ALL) and another patient with leukaemic generalization of B-cell lymphoma Auer bodies were found in a few immature cells. The diagnosis in both cases was based on clinical grounds, morphology, cytochemistry, and immunological marker analysis of the blasts. Auer bodies are known to be a marker of high significance for acute non-lymphocytic leukaemias. Therefore the findings described suggest mixed leukaemias with either T-cell or B-cell predominance. It provides further evidence for the existence of a common progenitor of myeloid and lymphoid cells.