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Auditory function associated with Col11a1 haploinsufficiency in chondrodysplasia (cho) mice

✍ Scribed by Yvonne M Szymko-Bennett; Kiyoto Kurima; Bjorn Olsen; Robert Seegmiller; Andrew J Griffith


Book ID
117534369
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
208 KB
Volume
175
Category
Article
ISSN
0378-5955

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## Abstract ## Objective To investigate whether heterozygosity for a loss‐of‐function mutation in the gene encoding the Ξ±1 chain of type XI collagen (__Col11a1__) in mice (chondrodysplasia, __cho__) causes osteoarthritis (OA), and to understand the biochemical and biomechanical effects of this mut