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Atypical movement disorders in antiphospholipid syndrome

✍ Scribed by Davide Martino; Nee-Kong Chew; Pablo Mir; Mark J. Edwards; Niall P. Quinn; Kailash P. Bhatia

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 107 KB
Volume: 21
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.20842

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✦ Synopsis

Abstract

Movement disorders have only rarely been reported in association with antiphospholipid syndrome (APS). In such cases, chorea is the most common disorder observed, with occasional reports of hemidystonia, Parkinsonism, and hemiballism. We report here on 3 cases of APS (3 women ages 16, 46, and 56 years) who presented with movement disorders, including tics, tremor, myoclonus, and a corticobasal syndrome, never or rarely reported in association with this disease. Mild executive dysfunction was observed in all 3 patients. We also report the successful treatment of two of these patients with mild oral anticoagulation (INR 2–3). Movement disorders in APS seem more clinically heterogeneous than previously thought. Oral anticoagulation should be considered in the treatment of movement disorders associated with APS. © 2006 Movement Disorder Society

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