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Atypical ductal hyperplasia and ductal carcinoma in situ of the breast associated with perineural invasion

✍ Scribed by Helenice Gobbi; Roy A Jensen; Jean F Simpson; Sandra J Olson; David L Page


Book ID
117818488
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
407 KB
Volume
32
Category
Article
ISSN
1532-8392

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MUC1 mucin is a high molecular weight transmembrane glycoprotein expressed on the apical cell surface of normal glandular epithelia. In many human adenocarcinomas, this protein is up-regulated and/or underglycosylated, and its expression changes from apical to the entire cell membrane. It is thought