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Attrition of T Cell Memory: Selective Loss of LCMV Epitope–Specific Memory CD8 T Cells following Infections with Heterologous Viruses

✍ Scribed by Liisa K Selin; Meei Y Lin; Kristy A Kraemer; Drew M Pardoll; Jonathan P Schneck; Steven M Varga; Paul A Santolucito; Amelia K Pinto; Raymond M Welsh


Book ID
117722576
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
202 KB
Volume
11
Category
Article
ISSN
1074-7613

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## Abstract The requirements for the conversion of CD8^+^ memory T cells into effector class I major histocompatibility complex (MHC) K^d^−restricted cytotoxic T (T~c~) cells __in vitro__ have been studied. Purified CD8^+^splenocytes from influenza A/WSN‐primed BALB/c (H‐2^d^) mice stimulated with