## Abstract The effects of combined administration of bombesin (40 ฮผ/kg body weight) and the ornithine decarboxylase (ODC) inhibitor, 1,3โdiaminopropane (DAP), on the development of large and small intestinal tumors and the incidence of their metastasis to the peritoneum induced by azoxymethane (AO
Attenuation of vasoactive intestinal peptide enhancement of colon carcinogenesis by ornithine decarboxylase inhibitor
โ Scribed by Masaharu Tatsuta; Hiroyasu Iishi; Miyako Baba; Reiko Yamamoto; Hiroyuki Uehara; Akihiko Nakaizumi
- Book ID
- 116123258
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 609 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0304-3835
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## Abstract The effects of combined administration of bombesin and the ornithine decarboxylase (ODC) inhibitor 1,3โdiaminopropane (DAP) on the incidence and number of gastric tumors induced by NโmethylโN'โnitroโNโnitrosoguanidine (MNNG), the ODC activity of the gastric wall and the labelling index
Involvement of ornithine decarboxylase (ODC) in proliferation of the HT29 cell line and its control by either fetal calf serum (FCS) or vasoactive intestinal peptide (VIP) as an external signal increasing CAMP level were investigated. Activation of the polyamine-producing system appears to be a nece