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Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists

✍ Scribed by Jaroslava Folbergrová; Renata Haugvicová; Pavel Mareš

Book ID
113997275
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
538 KB
Volume
908
Category
Article
ISSN
0006-8993

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While it is well documented that the overactivation of ionotropic glutamate receptors leads to seizures and excitotoxic injury, little is known about the role of metabotropic glutamate receptors (mGluRs) in epileptogenesis and neuronal injury. Intracerebroventricular (i.c.v.) infusion of the group I