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Attenuation of renal fibrosis by curcumin in rat obstructive nephropathy

✍ Scribed by Nobuyuki Kuwabara; Satoshi Tamada; Tomoaki Iwai; Kae Teramoto; Noriko Kaneda; Tokihito Yukimura; Tatsuya Nakatani; Katsuyuki Miura

Book ID: 116945499
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 455 KB
Volume: 67
Category: Article
ISSN: 0090-4295
DOI: 10.1016/j.urology.2005.09.028

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## Abstract **Scope**: We hypothesized that curcumin, a potent anti‐oxidant, might be beneficial in ameliorating the development of diabetic nephropathy through inhibition of PKC‐α and PKC‐β1 activity‐ERK1/2 pathway. **Methods and results**: Diabetes was induced by a single intraperitoneal injecti