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Attenuation of paraquat-induced motor behavior and neurochemical disturbances by l-valine in vivo

✍ Scribed by Thida Chanyachukul; Krongtong Yoovathaworn; Watchareewan Thongsaard; Sukumal Chongthammakun; Panida Navasumrit; Jutamaad Satayavivad

Book ID: 119377885
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 184 KB
Volume: 150
Category: Article
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2004.02.007

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## Abstract It has been demonstrated that L‐pipecolic acid (L‐PA), a major metabolic intermediate of L‐lysine (L‐Lys) in the mammalian and chicken brain, is involved in the functioning of the GABAergic system. A previous study has shown that intracerebroventricular (i.c.v.) injection of L‐PA suppre