𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Attenuation of pain and inflammation in adjuvant-induced arthritis by the proteasome inhibitor MG132

✍ Scribed by Aisha S. Ahmed; Jian Li; Mahmood Ahmed; Long Hua; Tatiana Yakovleva; Michael H. Ossipov; Georgy Bakalkin; André Stark

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
315 KB
Volume
62
Category
Article
ISSN
0004-3591

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The proteasome inhibitor bortezomib dras
The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant-induced arthritis in rats
✍ Evangelia Yannaki; Anastasia Papadopoulou; Evangelia Athanasiou; Panayotis Kaloy 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 791 KB

## Abstract ## Objective To explore the effect of bortezomib in splenocytes and fibroblast‐like synoviocytes (FLS) and its in vivo potency in a rat model of adjuvant‐induced arthritis (AIA), which resembles human rheumatoid arthritis (RA). ## Methods AIA was induced with Freund's complete adjuva

Stimulation of myofibrillar protein degr
Stimulation of myofibrillar protein degradation and expression of mRNA encoding the ubiquitin-proteasome system in C2C12 myotubes by dexamethasone: effect of the proteasome inhibitor MG-132
✍ Michael G. Thompson; Amanda Thom; Kris Partridge; Karen Garden; Gillian P. Campb 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 2 views

Addition of the synthetic glucocorticoid, dexamethasone (Dex) to serum-deprived C 2 C 12 myotubes elicited time-and concentration-dependent changes in Nmethylhistidine (3-MH), a marker of myofibrillar protein degradation. Within 24 h, 100 nM Dex significantly decreased the cell content of 3-MH and i

Prevention of the onset and progression
Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653
✍ Masataka Nishikawa; Akira Myoui; Tetsuya Tomita; Koichiro Takahi; Akihide Nampei 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 488 KB 👁 2 views

## Abstract ## Objective FR167653 is a potent inhibitor of p38 mitogen‐activated protein kinase (MAPK) and inhibits tumor necrosis factor α (TNFα) and interleukin‐1β (IL‐1β) production in inflammatory cells. In this study we investigated the effect of FR167653 on collagen‐induced arthritis (CIA).