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Attenuation of p53 Expression Protects Against Focal Ischemic Damage in Transgenic Mice

โœ Scribed by Thomas, Amy L.; Morgan, Philip F.; Christian Crumrine, R.


Book ID
109870729
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
241 KB
Volume
14
Category
Article
ISSN
0271-678X

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Tissue-specific expression of p53 in tra
โœ Guillermina Lozano; Arnold J. Levine ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 676 KB

Transgenic mice were produced harboring the p53 murine cDNA clone regulated by the SV40 enhancer-promoter region 5' to the cDNA and the small t antigen splice sites, and poly(A) addition signals 3' to the cDNA. This construction was not expressed in these mice. The presence of several murine p53 int