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Attenuation of hyperglycemia-mediated oxidative stress by indole-3-carbinol and its metabolite 3, 3′- diindolylmethane in C57BL/6J mice

✍ Scribed by Jayakumar, Poornima; Pugalendi, Kodukkur Vishwanath; Sankaran, Mirunalini

Book ID
125382954
Publisher
Springer
Year
2014
Tongue
English
Weight
1018 KB
Volume
70
Category
Article
ISSN
1138-7548

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The possible role of active metabolites of 3, 4, 3', 4'-tetrachlorobiphenyl (TCB) in causing thymic atrophy was investigated using inbred strains of mice. The generation of reactive species which bind covalently to cellular proteins was used to monitor the formation of active TCB metabolites. The am