j774A. 1 immortalized macrophage tumor cells display several phenotypes and functional capacities similar to that of murinc peritoneal exudate macrophages (PEM). Both populations display comparable number of M-CSF receptors. Yet the number of GM-CSF receptors on J774A.1 cells is only one-fourth that
Attenuation of airway hyperresponsiveness in a murine asthma model by neutralization of granulocyte–macrophage colony-stimulating factor (GM-CSF)
✍ Scribed by Naomi Yamashita; Hiroyuki Tashimo; Hirobumi Ishida; Fujito Kaneko; Junichi Nakano; Hiroshi Kato; Koichi Hirai; Tadashi Horiuchi; Ken Ohta
- Book ID
- 114008178
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 212 KB
- Volume
- 219
- Category
- Article
- ISSN
- 0008-8749
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## Abstract Seven days after subcutaneous injection of 2% carrageenin solution in mice, the induced inflammatory tissue was isolated and treated with 0.1% trypsin. When the dispersed cells were incubated in a nutrient medium containing 5‐‐20% calf serum, the cells grew adhering to the culture‐dish