Attenuation by electroconvulsive shock and antidepressant drugs of the 5-HT1Areceptor-mediated hypothermia and serotonin syndrome produced by 8-OH-DPAT in the rat

The enhancement by lithium of the 5-HT1A

The enhancement by lithium of the 5-HT1Amediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism

✍ G. M. Goodwin; R. J. Souza; A. J. Wood; A. R. Green 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 635 KB

Administration of lithium chloride (10 mmol/kg on day 1 and 3 mmol/kg twice daily on subsequent days, SC) for 3-14 days enhances the components of the serotonin syndrome produced by 8-hydroxy-2-(di-propylamino)tetralin (8-OH-DPAT) in the rat. The hypothermic response produced simultaneously was unal