Attenuated response to nomifensine in rats during a swim test following lesion of the habenula complex

Administration of baclofen, a γ-aminobut

Administration of baclofen, a γ-aminobutyric acid type B agonist in the thalamic ventrobasal complex, attenuates allodynia in monoarthritic rats subjected to the ankle-bend test

✍ Catarina Soares Potes; Fani Lourença Neto; José Manuel Castro-Lopes 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 286 KB

## Abstract γ‐Aminobutyric acid type B (GABA~B~) receptors are involved in the modulation of neuronal activity in response to chronic noxious input. However, the effect of their activation in chronic inflammatory pain in relay thalamic nuclei such as the ventrobasal complex (VB) is not known. In th