Attempt to purify the normal cellular isoform of prion protein from mouse and hamster brain

Semipreparative Chromatographic Method t

Semipreparative Chromatographic Method to Purify the Normal Cellular Isoform of the Prion Protein in Nondenatured Form

✍ Paola Pergami; Howard Jaffe; Jiri Safar 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 248 KB

Recent developments in the genetics and molecular A fundamental step in the pathogenesis of spongibiology of spongiform encephalopathies (prion disform encephalopathies (prion diseases) is the convereases) confirm the key role of prion protein (PrP Sc ) 2 in sion of the cellular isoform of prion pro