HMGA2 and the p19Arf-TP53-CDKN1A axis: A
✍
Dominique Nadine Markowski; Inga von Ahsen; Maliheh Hashemi Nezhad; Werner Wosni
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 231 KB
## Abstract Pathogenetically, uterine leiomyomas (ULs) can be interpreted as the result of a monoclonal abnormal proliferation of myometrial cells. Oncogene‐induced senescence (OIS) is a frequent phenomenon in premalignant lesions that leads to a growth arrest mainly by the activation of two potent