Atropo-enantioselective synthesis of a C3-symmetric tripodal ligand with three axially chiral biaryl subunits

✍ Scribed by Gerhard Bringmann; Matthias Breuning; Robert-Michael Pfeifer; Petra Schreiber

• Book ID: 104359916
• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 161 KB
• Volume: 14
• Category: Article
• ISSN: 0957-4166
• DOI: 10.1016/s0957-4166(03)00406-3

✦ Synopsis

In contrast to the numerous successful applications of C 2 -symmetric biaryls as powerful tools for asymmetric synthesis, there have so far been only few reports on combinations of C 3 -symmetry with axial chirality. We present here the first enantioselective synthesis of a novel family of tripodal ligands containing three axially chiral biaryl subunits in an (M,M,M)-or, optionally, (P,P,P)-configured form. The incorporation of a PCl 2 -and a TiCl-fragment into the central cavity was achieved.