ATP-sensitive potassium channels mediate the thermosensory response of orexin neurons
β Scribed by Matthew P. Parsons; Natasha Belanger-Willoughby; Victoria Linehan; Michiru Hirasawa
- Book ID
- 117968424
- Publisher
- Cambridge University Press
- Year
- 2012
- Tongue
- English
- Weight
- 1012 KB
- Volume
- 590
- Category
- Article
- ISSN
- 0022-3751
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The ATP-sensitive potassium channel (KATP channel) is a unique ionophore in that it appears to reflect cell metabolism. In the brain, the highest density of binding sites for the KATP channel is the substantia nigra. To evaluate the role of the KATP channel in this key brain area for motor control,
## Abstract Hyperglycemiaβrelated neuronal excitability and epileptic seizures are not uncommon in clinical practice. However, their underlying mechanism remains elusive. ATPβsensitive K^+^ (K~ATP~) channels are found in many excitable cells, including cardiac myocytes, pancreatic Ξ² cells, and neur