ATP levels in phosphate-deregulated and arsenate-resistant mutants of Streptomyces noursei
✍ Scribed by Dr. F. Hänel; U. Gräfe; W. Friedrich; E. J. Bormann
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 438 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0233-111X
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✦ Synopsis
ATP levels in phosphate-deregulated and arsenate-resistant mutants of Streptomyces noursei F. HANET,, u. GRAFE, W. Frt1E:nRIcH and E. J . RORMANN (Eingega.ngen am. 26.9. 1953) Mycelial levels of ATP and glucose-6-phosphate were investigated in mutants of streptothricinproducing AS. nowsei JA 3890b differing from the wild-type stra.in in mtibiotic formation, in thc control by inorganic phosphate of the secondary metabolism, and in the resistance to growth inhi-bit~ion by t,oxic arsenate ions. As compared with the ancestral strain, mutant's exhibited a lower cont'ent of ATP in the mycelium while addition of 0.1 M arsenate to growing cultures provoked