ATP-evoked calcium signal stimulates protein phosphorylation/dephosphorylation in astrocytes
โ Scribed by J.T. Neary; R. Laskey; C. van Breemen; J. Blicharska; L.O.B. Norenberg; M.D. Norenberg
- Book ID
- 115802438
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 802 KB
- Volume
- 566
- Category
- Article
- ISSN
- 0006-8993
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## Abstract NG2โglia are an abundant population of cells in the adult CNS that make up a novel glial cell type. Here, we have examined calcium signals in NG2โglia identified by expression of the fluorescent protein DsRed under the control of the NG2 promoter in the white matter of the mouse optic n
We have studied the interaction between P1 and P2 purinoceptors in purified type-1 astrocyte cultures from postnatal days 7-8 rat cerebella using single cell microfluorimetry with fura-2. The stimulation of astrocytes with ATP elicits rapid [Ca 2ฯฉ ] i transients showing an EC 50 value of 7.9 ฯฎ 0.3 ยต