ATP dependent primary active transport of xenobiotic-glutathione conjugates by human erythrocyte membrane

The inhibition of ATP-dependent shape ch

The inhibition of ATP-dependent shape change of human erythrocyte ghosts correlates with an inhibition of Mg2+-ATPase activity by fluoride and aluminofluoride complexes

✍ Michael B. Morris; Gregory Monteith; Basil D. Roufogalis 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 971 KB

The vanadate-sensitive Mg"-dependent ATPase activity of the human erythrocyte ghost is believed to be involved in the shape change events that convert echinocytic ghosts to smoothed forms (biconcave discs and stomatocytes). At physiological salt concentration, pH 7.4,2 m M ATP, 5 m M Mg2' and 1 m M