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Atorvastatin preconditioning attenuates the production of endothelin-1 and prevents experimental vasospasm in rats

✍ Scribed by Chih-Zen Chang; Shu-Chuan Wu; Chih-Long Lin; Shiuh-Lin Hwang; Shen-Long Howng; Aij-Lie Kwan


Publisher
Springer Vienna
Year
2010
Tongue
English
Weight
252 KB
Volume
152
Category
Article
ISSN
0001-6268

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The phosphodiesterase inhibitor pentoxifylline (POX), which is known to have pharmacological effects in animal models of multiorgan failure and endotoxinmediated shock, was tested for its immunosuppressive potential onT lymphocyte activation in vitro and in vivo. POX was found to have a profound inh